T57I (p.Thr57Ile) variant of FGG (Fibrinogen gamma chain)
T57I (p.Thr57Ile) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
T57I (p.Thr57Ile) variant details
- p.Thr57Ile
- ExAC rs748671641
- gnomAD rs748671641
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.35
- CADD 17.30
- PolyPhen-2 0.49
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available