S125L (p.Ser125Leu) variant of FGG (Fibrinogen gamma chain)
S125L (p.Ser125Leu) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S125L (p.Ser125Leu) variant details
- p.Ser125Leu
- ExAC rs200696007
- TOPMed rs200696007
- gnomAD rs200696007
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.13
- CADD 11.80
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the Latino/Admixed American population (allele frequency 0.00066)
- Structural context available