P7T (p.Pro7Thr) variant of FGG (Fibrinogen gamma chain)
P7T (p.Pro7Thr) in FGG (Fibrinogen gamma chain) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P7T (p.Pro7Thr) variant details
- p.Pro7Thr
- cosmic curated COSV60194
- ESP rs374845868
- ExAC rs374845868
- TOPMed rs374845868
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.04
- CADD 15.40
- PolyPhen-2 0.06
- SIFT 0.05
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available