L86R (p.Leu86Arg) variant of FGG (Fibrinogen gamma chain)
L86R (p.Leu86Arg) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
L86R (p.Leu86Arg) variant details
- p.Leu86Arg
- gnomAD rs1322998482
- Missense
- Variant Prioritization Score for Impact Estimate 0.533
- REVEL 0.50
- CADD 21.10
- PolyPhen-2 0.02
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available