L69S (p.Leu69Ser) variant of FGG (Fibrinogen gamma chain)
L69S (p.Leu69Ser) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L69S (p.Leu69Ser) variant details
- p.Leu69Ser
- TOPMed rs1731227050
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.66
- CADD 25.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available