L5W (p.Leu5Trp) variant of FGG (Fibrinogen gamma chain)
L5W (p.Leu5Trp) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
L5W (p.Leu5Trp) variant details
- p.Leu5Trp
- TOPMed rs984949115
- gnomAD rs984949115
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.07
- CADD 14.50
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available