I133T (p.Ile133Thr) variant of FGG (Fibrinogen gamma chain)
I133T (p.Ile133Thr) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
I133T (p.Ile133Thr) variant details
- p.Ile133Thr
- TOPMed rs1387232364
- gnomAD rs1387232364
- Missense
- Variant Prioritization Score for Impact Estimate 0.714
- REVEL 0.77
- CADD 25.20
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available