I11T (p.Ile11Thr) variant of FGG (Fibrinogen gamma chain)
I11T (p.Ile11Thr) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
I11T (p.Ile11Thr) variant details
- p.Ile11Thr
- gnomAD rs1205549450
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.07
- CADD 17.10
- PolyPhen-2 0.08
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available