E77K (p.Glu77Lys) variant of FGG (Fibrinogen gamma chain)
E77K (p.Glu77Lys) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
E77K (p.Glu77Lys) variant details
- p.Glu77Lys
- gnomAD rs1731226370
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.30
- CADD 15.90
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available