C49S (p.Cys49Ser) variant of FGG (Fibrinogen gamma chain)
C49S (p.Cys49Ser) in FGG (Fibrinogen gamma chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
C49S (p.Cys49Ser) variant details
- p.Cys49Ser
- gnomAD rs1198013337
- Missense
- Variant Prioritization Score for Impact Estimate 0.857
- REVEL 0.89
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available