A107T (p.Ala107Thr) variant of FGG (Fibrinogen gamma chain)
A107T (p.Ala107Thr) in FGG (Fibrinogen gamma chain) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A107T (p.Ala107Thr) variant details
- p.Ala107Thr
- 1000Genomes rs754465392
- ExAC rs754465392
- TOPMed rs754465392
- gnomAD rs754465392
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.21
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.61
- ClinVar: Uncertain significance (not provided)
- UniProt: Uncertain significance
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available