V28L (p.Val28Leu) variant of FGFR4 (P22455)
V28L (p.Val28Leu) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V28L (p.Val28Leu) variant details
- p.Val28Leu
- TOPMed rs979979470
- gnomAD rs979979470
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.10
- CADD 12.00
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available