V10G (p.Val10Gly) variant of FGFR4 (P22455)
V10G (p.Val10Gly) in FGFR4 (P22455) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V10G (p.Val10Gly) variant details
- p.Val10Gly
- NCI-TCGA TCGA novel
- gnomAD rs1400416973
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.39
- CADD 22.10
- PolyPhen-2 0.02
- SIFT 0.04
- UniProt: Variant assessed as somatic; high impact. (in dbSNP:rs1966265)
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available