T46I (p.Thr46Ile) variant of FGFR4 (P22455)
T46I (p.Thr46Ile) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T46I (p.Thr46Ile) variant details
- p.Thr46Ile
- ExAC rs746357877
- TOPMed rs746357877
- gnomAD rs746357877
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.29
- CADD 8.12
- PolyPhen-2 0.04
- SIFT 0.51
- Most common in the East Asian population (allele frequency 0.0005)
- Structural context available