S25F (p.Ser25Phe) variant of FGFR4 (P22455)
S25F (p.Ser25Phe) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
S25F (p.Ser25Phe) variant details
- p.Ser25Phe
- gnomAD 5-177089676-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.45
- CADD 24.50
- PolyPhen-2 0.96
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available