R59W (p.Arg59Trp) variant of FGFR4 (P22455)
R59W (p.Arg59Trp) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R59W (p.Arg59Trp) variant details
- p.Arg59Trp
- cosmic curated COSV52800
- 1000Genomes rs200344385
- ESP rs200344385
- ExAC rs200344385
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.42
- CADD 21.20
- PolyPhen-2 0.33
- SIFT 0.02
- Most common in the 1KG:JPT population (allele frequency 0.0098)
- Structural context available