R59L (p.Arg59Leu) variant of FGFR4 (P22455)
R59L (p.Arg59Leu) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R59L (p.Arg59Leu) variant details
- p.Arg59Leu
- ExAC rs751304047
- TOPMed rs751304047
- gnomAD rs751304047
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.23
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available