R2Q (p.Arg2Gln) variant of FGFR4 (P22455)
R2Q (p.Arg2Gln) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R2Q (p.Arg2Gln) variant details
- p.Arg2Gln
- cosmic curated COSV10941
- ESP rs141355998
- ExAC rs141355998
- TOPMed rs141355998
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.23
- CADD 1.02
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available