P15S (p.Pro15Ser) variant of FGFR4 (P22455)
P15S (p.Pro15Ser) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- cosmic curated COSV52811
- ExAC rs776518605
- TOPMed rs776518605
- gnomAD rs776518605
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.12
- CADD 9.10
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available