L8S (p.Leu8Ser) variant of FGFR4 (P22455)
L8S (p.Leu8Ser) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L8S (p.Leu8Ser) variant details
- p.Leu8Ser
- gnomAD 5-177089625-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.38
- CADD 20.20
- PolyPhen-2 0.19
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available