L7M (p.Leu7Met) variant of FGFR4 (P22455)
L7M (p.Leu7Met) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L7M (p.Leu7Met) variant details
- p.Leu7Met
- ExAC rs745509807
- TOPMed rs745509807
- gnomAD rs745509807
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.29
- CADD 8.74
- PolyPhen-2 0.33
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available