L49P (p.Leu49Pro) variant of FGFR4 (P22455)
L49P (p.Leu49Pro) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L49P (p.Leu49Pro) variant details
- p.Leu49Pro
- 1000Genomes rs780226734
- ExAC rs780226734
- gnomAD rs780226734
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.20
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available