L45P (p.Leu45Pro) variant of FGFR4 (P22455)
L45P (p.Leu45Pro) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
L45P (p.Leu45Pro) variant details
- p.Leu45Pro
- gnomAD 5-177090432-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.631
- REVEL 0.63
- CADD 24.80
- PolyPhen-2 0.85
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available