L45M (p.Leu45Met) variant of FGFR4 (P22455)
L45M (p.Leu45Met) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L45M (p.Leu45Met) variant details
- p.Leu45Met
- gnomAD 5-177090431-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.29
- CADD 20.50
- PolyPhen-2 0.80
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available