L34V (p.Leu34Val) variant of FGFR4 (P22455)
L34V (p.Leu34Val) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L34V (p.Leu34Val) variant details
- p.Leu34Val
- TOPMed rs922358662
- gnomAD rs922358662
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.20
- CADD 12.60
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available