L22R (p.Leu22Arg) variant of FGFR4 (P22455)
L22R (p.Leu22Arg) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L22R (p.Leu22Arg) variant details
- p.Leu22Arg
- gnomAD 5-177089667-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.27
- CADD 19.30
- PolyPhen-2 0.12
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available