L20F (p.Leu20Phe) variant of FGFR4 (P22455)
L20F (p.Leu20Phe) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L20F (p.Leu20Phe) variant details
- p.Leu20Phe
- gnomAD 5-177089662-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.18
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available