C56W (p.Cys56Trp) variant of FGFR4 (P22455)
C56W (p.Cys56Trp) in FGFR4 (P22455) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
C56W (p.Cys56Trp) variant details
- p.Cys56Trp
- ExAC rs762728948
- gnomAD rs762728948
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.60
- CADD 23.00
- PolyPhen-2 0.38
- SIFT 0.18
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available