S24F (p.Ser24Phe) variant of FGFR3 (P22607)
S24F (p.Ser24Phe) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S24F (p.Ser24Phe) variant details
- p.Ser24Phe
- cosmic curated COSV10502
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.19
- MetaLR 0.32
- MetaSVM -0.72
- CADD 18.80
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 6e-06)
- Structural context available