S22P (p.Ser22Pro) variant of FGFR3 (P22607)
S22P (p.Ser22Pro) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
S22P (p.Ser22Pro) variant details
- p.Ser22Pro
- gnomAD 4-1793998-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.15
- MetaLR 0.24
- MetaSVM -0.82
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available