S21T (p.Ser21Thr) variant of FGFR3 (P22607)
S21T (p.Ser21Thr) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S21T (p.Ser21Thr) variant details
- p.Ser21Thr
- gnomAD 4-1793995-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.09
- MetaLR 0.20
- MetaSVM -0.92
- CADD 2.17
- PolyPhen-2 0.00
- SIFT 0.84
- Population evidence available
- Structural context available
- Literature evidence available