L25W (p.Leu25Trp) variant of FGFR3 (P22607)
L25W (p.Leu25Trp) in FGFR3 (P22607) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L25W (p.Leu25Trp) variant details
- p.Leu25Trp
- gnomAD 4-1794004-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.224
- CADD 20.20
- Population evidence available
- Structural context available
- Literature evidence available