L25S (p.Leu25Ser) variant of FGFR3 (P22607)
L25S (p.Leu25Ser) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
L25S (p.Leu25Ser) variant details
- p.Leu25Ser
- gnomAD 4-1794008-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.16
- MetaLR 0.23
- MetaSVM -0.87
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 0.17
- Population evidence available
- Structural context available
- Literature evidence available