L25M (p.Leu25Met) variant of FGFR3 (P22607)
L25M (p.Leu25Met) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- cosmic curated COSV53396
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.30
- MetaLR 0.36
- MetaSVM -0.68
- CADD 11.60
- PolyPhen-2 0.02
- SIFT 0.22
- Population evidence available
- Structural context available