G26W (p.Gly26Trp) variant of FGFR3 (P22607)
G26W (p.Gly26Trp) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
G26W (p.Gly26Trp) variant details
- p.Gly26Trp
- gnomAD 4-1794010-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.25
- MetaLR 0.39
- MetaSVM -0.67
- CADD 23.50
- PolyPhen-2 0.52
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available