C11Y (p.Cys11Tyr) variant of FGFR3 (P22607)
C11Y (p.Cys11Tyr) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
C11Y (p.Cys11Tyr) variant details
- p.Cys11Tyr
- gnomAD 4-1793966-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.17
- MetaLR 0.20
- MetaSVM -0.87
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available