A3P (p.Ala3Pro) variant of FGFR3 (P22607)
A3P (p.Ala3Pro) in FGFR3 (P22607) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A3P (p.Ala3Pro) variant details
- p.Ala3Pro
- gnomAD rs1259385466
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.26
- MetaLR 0.26
- MetaSVM -0.71
- CADD 14.90
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available