T17I (p.Thr17Ile) variant of FGFR2 (P21802)
T17I (p.Thr17Ile) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T17I (p.Thr17Ile) variant details
- p.Thr17Ile
- ExAC rs766435280
- TOPMed rs766435280
- gnomAD rs766435280
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.37
- CADD 23.40
- PolyPhen-2 0.30
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available