L33I (p.Leu33Ile) variant of FGFR2 (P21802)
L33I (p.Leu33Ile) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L33I (p.Leu33Ile) variant details
- p.Leu33Ile
- TOPMed rs1298138650
- gnomAD rs1298138650
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.10
- CADD 7.17
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available