L18W (p.Leu18Trp) variant of FGFR2 (P21802)
L18W (p.Leu18Trp) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L18W (p.Leu18Trp) variant details
- p.Leu18Trp
- TOPMed rs1863027871
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.43
- CADD 24.70
- PolyPhen-2 0.39
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available