L18V (p.Leu18Val) variant of FGFR2 (P21802)
L18V (p.Leu18Val) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L18V (p.Leu18Val) variant details
- p.Leu18Val
- cosmic curated COSV60646
- TOPMed rs1863028330
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.11
- CADD 11.00
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available