L18S (p.Leu18Ser) variant of FGFR2 (P21802)
L18S (p.Leu18Ser) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L18S (p.Leu18Ser) variant details
- p.Leu18Ser
- TOPMed rs1863027871
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.30
- CADD 22.10
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available