L10V (p.Leu10Val) variant of FGFR2 (P21802)
L10V (p.Leu10Val) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- ESP rs370122049
- ExAC rs370122049
- gnomAD rs370122049
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.37
- CADD 21.00
- PolyPhen-2 0.15
- SIFT 0.30
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available