L10P (p.Leu10Pro) variant of FGFR2 (P21802)
L10P (p.Leu10Pro) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- TOPMed rs1863033429
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.65
- CADD 27.10
- PolyPhen-2 0.71
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available