F25L (p.Phe25Leu) variant of FGFR2 (P21802)
F25L (p.Phe25Leu) in FGFR2 (P21802) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- Ensembl rs2135483472
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.30
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.91
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available