R22T (p.Arg22Thr) variant of FGFR1 (P11362)
R22T (p.Arg22Thr) in FGFR1 (P11362) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R22T (p.Arg22Thr) variant details
- p.Arg22Thr
- Ensembl rs2151342815
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- REVEL 0.57
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available