P33T (p.Pro33Thr) variant of FGFR1 (P11362)
P33T (p.Pro33Thr) in FGFR1 (P11362) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes structural context.
P33T (p.Pro33Thr) variant details
- p.Pro33Thr
- rs1371683958
- ClinGen CA370736658
- ClinVar RCV003147252
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- AlphaMissense 0.07
- MetaLR 0.32
- MetaSVM -0.66
- PolyPhen-2 0.00
- SIFT 0.06
- MutPred 0.45
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available