P33S (p.Pro33Ser) variant of FGFR1 (P11362)
P33S (p.Pro33Ser) in FGFR1 (P11362) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- TOPMed rs1371683958
- gnomAD rs1371683958
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.19
- AlphaMissense 0.07
- MetaLR 0.32
- MetaSVM -0.66
- CADD 22.50
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available