P25T (p.Pro25Thr) variant of FGFR1 (P11362)
P25T (p.Pro25Thr) in FGFR1 (P11362) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
P25T (p.Pro25Thr) variant details
- p.Pro25Thr
- Ensembl rs1833137533
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.29
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.46
- ClinVar: Uncertain significance (not provided)
- UniProt: Uncertain significance
- Population evidence available
- Structural context available