L8F (p.Leu8Phe) variant of FGFR1 (P11362)
L8F (p.Leu8Phe) in FGFR1 (P11362) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
L8F (p.Leu8Phe) variant details
- p.Leu8Phe
- cosmic curated COSV10736
- TOPMed rs1259538191
- gnomAD rs1259538191
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.43
- CADD 22.60
- PolyPhen-2 0.19
- SIFT 0.20
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available